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Changes to the Roche Corporate Executive Committee 28 January 2016

Silvia Ayyoubi (62), Head of Group Human Resources for Roche and member of the Corporate Executive Committee has decided to retire from Roche following the Annual General Meeting in March 2016. Silvia Ayyoubi joined Roche in 1987 and held several positions of growing responsibility in human resources. She has been Head of Group Human Resources and a member of the Corporate Executive Committee since March 2008.

The Board of Directors has appointed Cristina Wilbur (48) to succeed Silvia Ayyoubi as Head of Group Human Resources and member of the Corporate Executive Committee. Cristina Wilbur, currently Head of Human Resources for the Diagnostics Division, joined Roche in Indianapolis, US, in 2002.

From 2006 until 2010 she was the Head of Human Resources for the Diagnostics organization in the United States. She has been holding her current position based in Basel, Switzerland, since the beginning of 2010. Cristina Wilbur holds a Bachelor of Science Degree in Business Administration and has more than twenty years of experience in business and human resources.